Cascade fluorofunctionalisation of 2,3-unsubstituted indoles by means of electrophilic fluorination.
نویسندگان
چکیده
Cascade fluorofunctionalisation of 2,3-unsubstituted indoles featuring the formation of C-C, C-F and C-O bonds via electrophilic fluorination using N-fluorobenzenesulfonimide is described. The use of an O-nucleophile tethered to the nitrogen of indoles enables the synthesis of polycyclic fluorinated indoline derivatives from simple precursors in 40-63% yields.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 90 شماره
صفحات -
تاریخ انتشار 2013